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Issue 35, 2015
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Micrometer-sized network structure of novel DNA–lipid conjugates induced by heat stimulation

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Abstract

We have developed a novel lipid-bearing DNA that forms hairpin modules, including a single RNA monomer; this can be used to create micrometer-sized structures from nanometer-sized building blocks during breakage at the RNA site. In the presence of divalent metal ions and heat stimulation, we observed transition of the self-assembly, which results in the formation of a three-dimensional network structure. To our knowledge, this is also the first report of heat-induced micrometer-sized molecular self-assembly of molecules that carry biological information.

Graphical abstract: Micrometer-sized network structure of novel DNA–lipid conjugates induced by heat stimulation

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Publication details

The article was received on 11 Jun 2015, accepted on 25 Jul 2015 and first published on 07 Aug 2015


Article type: Paper
DOI: 10.1039/C5SM01456E
Author version available: Download Author version (PDF)
Citation: Soft Matter, 2015,11, 7053-7058
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    Micrometer-sized network structure of novel DNA–lipid conjugates induced by heat stimulation

    K. Takahashi, M. Matsuo, T. Banno and T. Toyota, Soft Matter, 2015, 11, 7053
    DOI: 10.1039/C5SM01456E

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