Facile fabrication of pH-sensitive peptide–inorganic hollow spheres using a template-free method

Huiqin Yang; Deqiang Chen; Ruiqiu Xiao; Hongzhen Guo; Xiang Liu; Huali Nie

doi:10.1039/C7TB00523G

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Facile fabrication of pH-sensitive peptide–inorganic hollow spheres using a template-free method†

Huiqin Yang,^ab Deqiang Chen,^b Ruiqiu Xiao,^b Hongzhen Guo,^b Xiang Liu^b and Huali Nie

*^ab

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* Corresponding authors

^a Key Laboratory of Textile Science & Technology, Ministry of Education, Donghua University, Shanghai, P. R. China

^b College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai, P. R. China
E-mail: niehuali@dhu.edu.cn

Abstract

The self-assembly of a heptapeptide and phosphotungstic acid into hollow spheres with pH-responsive properties was successfully achieved using a template-free method. The release of the model drug doxorubicin from these spheres was found to be highly pH sensitive, giving them great potential for targeted drug delivery.

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Article information

DOI: https://doi.org/10.1039/C7TB00523G
Article type: Communication
Submitted: 22 Feb 2017
Accepted: 18 May 2017
First published: 19 May 2017

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J. Mater. Chem. B, 2017,5, 4569-4573

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Facile fabrication of pH-sensitive peptide–inorganic hollow spheres using a template-free method

H. Yang, D. Chen, R. Xiao, H. Guo, X. Liu and H. Nie, J. Mater. Chem. B, 2017, 5, 4569 DOI: 10.1039/C7TB00523G

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Journal of Materials Chemistry B

Facile fabrication of pH-sensitive peptide–inorganic hollow spheres using a template-free method†

Abstract

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Facile fabrication of pH-sensitive peptide–inorganic hollow spheres using a template-free method

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