Nanogel-loading a triarylboron-based AIE fluorophore to achieve ratiometric sensing for hydrogen peroxide and sequential response for pH

Abstract

By loading a triarylboron-based AIE Fluorophore, TNPB, on polyurethane nanogel (NG-TNPB), we achieved a ratiometric readout for sensing H₂O₂. PTBN-1-ol, produced by TNPB reacting with H₂O₂, can also make a sequential response for pH with the nanogel. We also applied NG-TNPB to detect H₂O₂ and provide a sequential response to pH in cells.