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Issue 74, 2016
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Number-controlled spatial arrangement of gold nanoparticles with DNA dendrimers

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Abstract

In this study we described a controlled self-assembly of gold nanoparticles mediated by DNA dendrimers. Stepwise titration of three-arm Y-shaped DNA monomers through a divergent route can assemble different generations of DNA dendrimers with discrete DNA sticky ends on the surface. Hybridizing gold nanoparticles bearing one single-stranded DNA to different generations of DNA dendrimers thereby results in assembly of number-controlled discrete gold nanoparticle groupings. The conjugation strategy used herein provides a novel model for spatial positioning of functionalized nanoparticles and precise construction of multivalent nanomaterials.

Graphical abstract: Number-controlled spatial arrangement of gold nanoparticles with DNA dendrimers

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Publication details

The article was received on 28 Jun 2016, accepted on 20 Jul 2016 and first published on 20 Jul 2016


Article type: Communication
DOI: 10.1039/C6RA16653A
Citation: RSC Adv., 2016,6, 70553-70556
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    Number-controlled spatial arrangement of gold nanoparticles with DNA dendrimers

    P. Chen, T. Zhang, T. Zhou and D. Liu, RSC Adv., 2016, 6, 70553
    DOI: 10.1039/C6RA16653A

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