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Issue 20, 2016
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A novel viscoelastic-based ferrofluid for continuous sheathless microfluidic separation of nonmagnetic microparticles

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Abstract

Separation of microparticles has found broad applications in biomedicine, industry and clinical diagnosis. In a conventional aqueous ferrofluid, separation of microparticles usually employs a sheath flow or two offset magnets to confine particle streams for downstream particle sorting. This complicates the fluid control, device fabrication, and dilutes the particle sample. In this work, we propose and develop a novel viscoelastic ferrofluid by replacing the Newtonian base medium of the conventional ferrofluid with non-Newtonian poly(ethylene oxide) (PEO) aqueous solution. The properties of both viscoelastic 3D focusing and negative magnetophoresis of the viscoelastic ferrofluid were verified and investigated. By employing the both properties in a serial manner, continuous and sheathless separation of nonmagnetic particles based on particle size has been demonstrated. This novel viscoelastic ferrofluid is expected to bring more flexibility and versatility to the design and functionality in microfluidic devices.

Graphical abstract: A novel viscoelastic-based ferrofluid for continuous sheathless microfluidic separation of nonmagnetic microparticles

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Publication details

The article was received on 07 Aug 2016, accepted on 19 Sep 2016 and first published on 19 Sep 2016


Article type: Paper
DOI: 10.1039/C6LC01007E
Citation: Lab Chip, 2016,16, 3947-3956
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    A novel viscoelastic-based ferrofluid for continuous sheathless microfluidic separation of nonmagnetic microparticles

    J. Zhang, S. Yan, D. Yuan, Q. Zhao, S. H. Tan, N. Nguyen and W. Li, Lab Chip, 2016, 16, 3947
    DOI: 10.1039/C6LC01007E

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